A NOVEL APPROACH TO CERULOPLASMIN STABILITY: PUTTING PROTEASE INHIBITORS INTO PRACTICE

Authors

  • Polyarush Svetlana Vitalievna
  • Ryskulov Farrukh Junior Researcher, II&HG, Tashkent, Uzbekistan
  • Masaidova Iroda Bаkhtier kizi Junior Researcher, II&HG, Tashkent, Uzbekistan

Keywords:

Ceruloplasmin, Proteolysis, Protease inhibitors, Enzyme-linked immunosorbent assay (ELISA), Biochemical spectrophotometry, Copper metabolism, Diagnosis, Protein stability, Pathology, Inflammatory processes.

Abstract

Ceruloplasmin (CP) is a multi-subunit protein that is central to copper metabolism in the human body [7; Р. 722–732]. This protein not only performs a transport function by delivering copper to tissues, but also serves as an important marker of inflammatory processes and pathologies associated with impaired copper metabolism [3; Р. 6904–6910, 8; Р. 27–36]. Additional studies have shown that plasma ceruloplasmin levels can be altered in a variety of diseases, including hereditary and autoimmune disorders [5; Р. 887–905]. This emphasises the critical importance of accurate quantification of its levels in clinical practice, as these data can have a significant impact on diagnosis and subsequent treatment [1; Р. 1–18].

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Published

2024-12-07

How to Cite

Polyarush Svetlana Vitalievna, Ryskulov Farrukh, & Masaidova Iroda Bаkhtier kizi. (2024). A NOVEL APPROACH TO CERULOPLASMIN STABILITY: PUTTING PROTEASE INHIBITORS INTO PRACTICE. British Journal of Global Ecology and Sustainable Development, 35, 1–6. Retrieved from https://journalzone.org/index.php/bjgesd/article/view/658

Issue

Vol. 35 (2024)

Section

Articles

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