EFFECT OF CALPASTATIN AND MYOSTATIN GENES ON THE ACTIVITY OF TRANSAMINATION ENZYMES IN SHEEP BLOOD SERUM

Authors

  • Urinboeva Maftuna Makhmudjonovna Research Institute of Karakul Breeding and Desert Ecology

Keywords:

Sheep, Karakul sheep, Jaydara sheep, Hissar sheep, CAST gene, MSTN gene, calpastatin, myostatin, AST, ALT, transamination enzymes, genotype, protein metabolism, molecular genetics, marker-assisted selection.

Abstract

This study investigated the influence of calpastatin (CAST) and myostatin (MSTN) gene polymorphisms on the activity of serum transamination enzymes in Karakul, Jaydara, and Hissar lambs. The activities of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were evaluated in animals with different genotypes. The results demonstrated that lambs carrying the N allele of the CAST and MSTN genes exhibited relatively higher AST and ALT activities compared with other genotypes. These findings indicate a significant relationship between these genetic markers and protein metabolism, as well as their potential association with meat productivity traits. The obtained results may serve as a scientific basis for the application of marker-assisted selection programs in sheep breeding.

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Published

2026-05-31

Issue

Vol. 52 (2026)

Section

Articles

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How to Cite

EFFECT OF CALPASTATIN AND MYOSTATIN GENES ON THE ACTIVITY OF TRANSAMINATION ENZYMES IN SHEEP BLOOD SERUM. (2026). British Journal of Global Ecology and Sustainable Development, 52, 42-47. https://journalzone.org/index.php/bjgesd/article/view/844